Janusz Rak Selected Research

Thromboplastin (Tissue Factor)

1/2021	Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles.
6/2019	Oncogenes and Clotting Factors: The Emerging Role of Tumor Cell Genome and Epigenome in Cancer-Associated Thrombosis.
1/2019	Mapping Subpopulations of Cancer Cell-Derived Extracellular Vesicles and Particles by Nano-Flow Cytometry.
12/2017	Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.
12/2017	Inhibition of tissue factor signaling in breast tumour xenografts induces widespread changes in the microRNA expression profile.
2/2016	Tissue Factor Regulation by miR-520g in Primitive Neuronal Brain Tumor Cells: A Possible Link between Oncomirs and the Vascular Tumor Microenvironment.
1/2015	Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day.
11/2014	The contribution of tumor and host tissue factor expression to oncogene-driven gliomagenesis.
10/2014	Brain neoplasms and coagulation-lessons from heterogeneity.
5/2014	Oncogenes and the coagulation system--forces that modulate dormant and aggressive states in cancer.

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Janusz Rak Research Topics

Disease

86	Neoplasms (Cancer) 01/2022 - 04/2002
12	Thrombosis (Thrombus) 01/2021 - 07/2002
11	Glioma (Gliomas) 01/2021 - 05/2008
11	Neoplasm Metastasis (Metastasis) 01/2021 - 02/2004
10	Hypoxia (Hypoxemia) 01/2022 - 10/2003
10	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 08/2010
9	Brain Neoplasms (Brain Tumor) 12/2019 - 01/2012
4	Inflammation (Inflammations) 04/2016 - 11/2006
4	Disease Progression 02/2016 - 04/2004
3	Breast Neoplasms (Breast Cancer) 01/2022 - 12/2017
3	Lewis Lung Carcinoma 09/2014 - 10/2003
3	Fibrosarcoma 10/2005 - 08/2003
2	Prostatic Neoplasms (Prostate Cancer) 04/2022 - 12/2017
2	Photosensitivity Disorders (Photodermatitis) 02/2019 - 07/2015
2	Medulloblastoma 02/2016 - 01/2012
2	Atherosclerosis 09/2014 - 10/2007
2	Colorectal Neoplasms (Colorectal Cancer) 11/2013 - 02/2013
2	Tics (Tic) 04/2012 - 12/2009
2	Thrombophilia 03/2009 - 02/2006
2	Hemorrhage 01/2008 - 07/2002
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2004 - 10/2002
1	Venous Thromboembolism 01/2022
1	Infections 01/2020
1	Rhabdoid Tumor (Rhabdoid Tumors) 01/2020
1	Aneuploidy (Aneuploid) 01/2020
1	Retinoblastoma (Glioblastoma, Retinal) 01/2019
1	Circulating Neoplastic Cells 01/2019
1	Small Cell Carcinoma 01/2019
1	Ovarian Neoplasms (Ovarian Cancer) 01/2019
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019

Drug/Important Bio-Agent (IBA)

28	Thromboplastin (Tissue Factor)IBA 01/2021 - 02/2004
20	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2005
16	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2012
16	ErbB Receptors (EGF Receptor)IBA 06/2019 - 10/2002
11	epidermal growth factor receptor VIIIIBA 01/2021 - 05/2008
10	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2009
10	Biological ProductsIBA 06/2019 - 01/2008
6	Hemostatics (Antihemorrhagics)IBA 01/2022 - 02/2004
6	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 04/2004
6	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2013 - 04/2002
5	CoagulantsIBA 06/2019 - 10/2014
5	MicroRNAs (MicroRNA)IBA 12/2018 - 01/2012
5	Thrombospondin 1IBA 04/2013 - 08/2003
4	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 01/2018
4	Oncogene Proteins (Oncogene Protein)IBA 01/2019 - 11/2010
4	Messenger RNA (mRNA)IBA 12/2017 - 10/2002
4	AnticoagulantsIBA 11/2013 - 07/2002
3	RNA (Ribonucleic Acid)IBA 01/2021 - 08/2016
3	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 06/2005
3	ProteomeIBA 01/2020 - 10/2013
3	Cyclin D1IBA 01/2020 - 01/2019
3	Pharmaceutical PreparationsIBA 12/2017 - 08/2013
3	LipidsIBA 01/2017 - 05/2008
3	Angiogenesis InhibitorsIBA 10/2005 - 10/2003
2	ChromatinIBA 01/2020 - 01/2019
2	Blood Coagulation Factors (Coagulation Factor)IBA 06/2019 - 01/2019
2	Heparin (Liquaemin)FDA LinkGeneric 12/2017 - 07/2002
2	Monoclonal AntibodiesIBA 12/2017 - 02/2004
2	Factor VII (Proconvertin)IBA 12/2017 - 04/2010
2	Trastuzumab (Herceptin)FDA Link 12/2017 - 07/2010
2	FibrinIBA 02/2016 - 12/2009
2	Cetuximab (Erbitux)FDA Link 10/2015 - 02/2004
2	Canertinib (CI 1033)IBA 10/2015 - 07/2010
2	tyrosine receptor (receptor, tyrosine)IBA 10/2015 - 07/2010
2	Phosphotransferases (Kinase)IBA 10/2015 - 07/2010
2	Apolipoproteins E (ApoE)IBA 09/2014 - 10/2007
2	Peptide Hydrolases (Proteases)FDA Link 01/2013 - 12/2009
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2008 - 10/2007
2	Antimitotic AgentsIBA 10/2007 - 10/2002
1	5-thiocyanato-2'-deoxyuridineIBA 04/2022
1	Radiation-Sensitizing AgentsIBA 01/2022
1	NucleosidesIBA 01/2022
1	Histones (Histone)IBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Bromodeoxyuridine (BrdU)IBA 01/2022
1	Steryl-Sulfatase (Steroid Sulfatase)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	CalciumIBA 01/2021
1	ethylisopropylamiloride (EIPA)IBA 01/2021
1	fibrin fragment D (D-dimer)IBA 01/2021
1	Histone Deacetylase InhibitorsIBA 01/2021
1	Platelet Factor 4IBA 01/2021
1	CytokinesIBA 12/2020
1	Matrix Metalloproteinases (MMPs)IBA 09/2020
1	EnzymesIBA 09/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2020
1	Phosphates (Orthophosphate)IBA 01/2020
1	GuanineIBA 01/2020
1	CytosineIBA 01/2020
1	ZR2002IBA 12/2019
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 06/2019
1	Bromouracil (5 Bromouracil)IBA 02/2019
1	Alkylating AgentsIBA 01/2019
1	Circulating Tumor DNAIBA 01/2019
1	IntegrinsIBA 01/2019

Therapy/Procedure

20	Therapeutics 01/2022 - 02/2004
6	Drug Therapy (Chemotherapy) 01/2021 - 04/2002
4	Radiotherapy 01/2022 - 12/2017
2	Photochemotherapy (Photodynamic Therapy) 02/2019 - 07/2015
1	Immunotherapy 01/2019